|Laboratory of Human Genome Research, Ministry of Public Health, P.R China|
Laboratory of Human Genome Research, Ministry of PublicHealth, P.R China & Shanghai Municipal Laboratory of HumanGenome Research (Lab for short) was approved officially by ShanghaiMunicipal Government in September 1993 and by Ministry of Health inOctober 1994.The research orientation of the Lab centers on solvingthe key scientific problems in life and medical sciences, andintegrating the latest scientific achievements of genomics into themedical practice. Over the past years, a series of technologicalplatforms of genomics including large-scale genomic sequencing andgenotyping, DNA mutation detection, biochips for tranome andproteome analysis, large-scale transgenics and knockout modelorganisms and bioinformatics were implemented. With the malignantcancers such as leukemia and other human diseases with highprevalence in China such as primary hypertension and type IIdiabetes as the objects for study, the Lab is focusing on thelocalization and identification of disease-related genes and thecharacterization of the regulatory pathways and network of theirprotein products. In the meantime, the Lab has been developingmolecular mechanism-based new methods of disease prevention,diagnosis and treatment, in order to improve health and advance thenation’s capability of prevention and cure of diseases.During1995-April 2009, the Lab had over 200 papers published on the corejournals, such as《Science》, 《NatureGenetics》,《PNAS》,《Blood》,《Oncogene》 and《Leukemia》. Furthermore, theLab has formed wide collaboration with scientific organizations inmany countries and regions such as USA, UK, France, Japan and HongKong.The Lab has a strong and high-level research team whichincludes a member of Chinese Academy of Sciences, 2 members ofChinese Academy of Engineering, 7 winners of National DistinguishedYoung Scholars Award of National Natural Science Foundation ofChina, 3 specially engaged professors of “Cheung Kong ScholarsProgram” of National Ministry of Education.
197 Rui-Jin Er Road， Shanghai 200025,China
1975-1977:Undergraduate study in Shangrao Medical School,
1) Leukemiasystems biology
1996: HLHLAward for Science and Technology, China
1. Zhang SJ,Ma LY, Huang QH, Li G, Gu BW, Gao XD, Shi JX, Wang YY,
Gao L, CaiX, Ren RB, Zhu J, Chen Z, Chen SJ. Gain-of-function
mutation ofGATA-2 in acute myeloid transformation of chronic
myeloid leukemia.Proc Natl Acid Sci USA 2008;105:2076-2081.